After Ryan (Elijah Wood) has an unsuccessful overdose attempt, he starts to see his neighbor’s dog Wilfred as a man in a dog suit. This Wilfred has been called a mixed breed: part labrador retriever, part Russell Crowe on a bender.
Calvin is an adventurous six-year-old boy with poor grades but a sharp wit. His best friend is Hobbes, a sarcastic tiger not afraid to give Calvin a dose of reality. Strangely, others seem to see Hobbes only as a stuffed toy.