Death from Sandman

In the DC comic series The Sandman, Death is both the end of life and the guider of souls. Unlike most personifications of death, like the Grim Reaper, she is a young goth woman dressed in casual clothes who also visits people as they are born.

Izaya Orihara

In DuRaRaRa!!, Izaya Orihara is a powerful information broker who deals information for his own enjoyment. He claims to love all of humanity with one exception — Shizuo Heiwajima.

Hestia

In Is It Wrong to Try to Pick Up Girls in a Dungeon? (or DanMachi for short), Hestia is a goddess who’s charged with watching over the young adventurer Bell Crannell. When he develops feelings for other girls, she can’t help but feel jealous, though she never lets that get in the way of her duty.

Green Goblin

In Spider-Man 3, Harry Osborn (James Franco) is the dedicated son of Norman Osborn. Believing that his father was murdered by Spider-Man, and because Spider-Man is really his best friend Peter Parker, Harry decides to battle him directly as the new Green Goblin.

Peggy Carter

In Captain America: The First Avenger, Peggy Carter (Hayley Atwell) is an officer of Great Britain’s Strategic Scientific Reserve. She splits her time between firing a machine gun at Nazis and falling in love with Captain America. All this before being promoted to an agent of SHIELD.

Barney Calhoun

Barney Calhoun is a playable character in Half-Life: Blue Shift, and a major character in Half-Life 2 as well as Episode One. Starting out as a security guard at Black Mesa Research Facility, he eventually joins the Lambda Resistance and works as a mole in the Combine Civil Protection Forces.

Winry Rockbell

In Fullmetal Alchemist, Winry Rockbell is a teenage mechanic who specializes in prostheses called automail, ensuring that Ed Elric’s replacement arm and leg are always in good working condition.

Space Dandy

In Space Dandy, Dandy is the dandy captain of the Aloha Oe, who hunts aliens with the help of his robot assistant QT and cat-like mate Meow. Unbeknownst to him, he’s also being hunted by Dr. Gel of the Gogol Empire.

Pvt. Vasquez

In Aliens, Private Jeanette Vasquez (Jenette Goldstein) is a smartgun operator who’s sent by the Marine Corps to deal with a space colony’s Xenomorph infestation. She’s tough as nails and doesn’t take crap from anyone, a useful skill when you’re in the same squad as Private Hudson.

Roman Torchwick

In RWBY, Roman Torchwick may be a fugitive criminal, but that doesn’t stop him from being a formal gentleman. His cane is indispensable, used as a melee weapon, firearm, and grappling hook all at once. His bowler hat and cane are a nod to A Clockwork Orange