In Metal Gear Solid V: The Phantom Pain, Quiet (voiced by Stefanie Joosten) is an AI sniper with supernatural abilities that Snake can call upon to assist him on missions. As her name suggests, she doesn’t talk much, but she can get the job done.

In the Uncharted series, Nathan “Nate” Drake is treasure hunter with an everyman personality and a wardrobe to match. Game publisher Naughty Dog based him on a combination of Johnny Knoxville and Harrison Ford, and they got the scoundrel down pat.

In this 2013 reboot of the Tomb Raider franchise, Lara Croft is a young and ambitious archaeologist on a quest to find the lost kingdom of Yamatai. She’s added new skills to her repertoire, including stealthing, ziplining, and shooting a bow and arrows. She’s also looking more like a grungy survivalist than ever before.

In Resident Evil, Jill Valentine is an explosives expert who’s worked with the U.S. Army and the Raccoon Police Department. In RE3: Nemesis, she’s forced to partner with an ex-member of the Umbrella Corporations paramilitary force in order to escape Raccoon City before a nuke strikes it.

In the Portal games, Chell is essentially a lab rat for Aperture Science, performing tests under the supervision of the AI bot GLaDOS. It’s not long before Chell sees her chance to escape the testing facility using her portal gun.

In the Metal Gear Solid series, Solid Snake is special ops agent who infiltrates enemy installations and disrupts their operations. When he’s vastly outnumbered, he’ll do whatever it takes to remain stealthy, and isn’t above camping out in a cardboard box.