Psycho Mantis is one of the most iconic villains of the Metal Gear series of video games. Psycho Mantis was a member of FOXHOUND led by Liquid Snake who possessed strong psychic abilities and grew up as a child soldier of XOF. He appears as a child in a small but crucial role in Metal Gear Solid V: Ground Zeroes and Metal Gear Solid V: The Phantom Pain as one of the potential controlling forces of the overall story.

Liquid Ocelot was Liquid Snake’s doppelgänger and Solid Snake’s final nemesis, appearing in Metal Gear Solid 2 as a minor villain and Metal Gear Solid 4 as the main villain. He is an alter ego of Revolver Ocelot caused after fusing with Liquid Snake’s arm and engaging in hypnotherapy. In MGS4, he creates the Outer Heaven PMC to take on The Patrots.

Meryl Silverburgh is one of the main characters of Metal Gear Solid 1 and Guns of the Patriots. She helps Solid Snake during the Shadow Moses incident and commands the Rat Patrol Team 01 of the CID During the Guns of the Patriots Incident and later becomes the wife of Johnny Sasaki.

In Metal Gear Solid, Punished “Venom” Snake is a mercenary commander who led Diamond Dogs and Outer Heaven as one of Big Boss’ most trusted lieutenants. As a medic, he saved Big Boss’s life, losing his left arm and right eye in the process, eventually taking on his identity.

In The Hateful Eight, Daisy Domergue (Jennifer Jason Leigh) is a fugitive captured by bounty hunter John “The Hangman” Ruth, who is intent to bringing her not dead, but alive. What’s worse, they’re accompanies by a second bounty hunter, Major Marquis Warren. They’re delayed however when a blizzard forces them to take refuge in a small stagecoach lodge.

In Metal Gear Solid, Kazuhira Miller is the subcommander of both the Militaires Sans Frontières and Diamond Dogs, and later, the survival trainer of FOXHOUND. He is well-read and possesses a vast array of scientific knowledge.